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Peripheral inflammation influences the CNS without crossing the bloodbrain barrier (BBB) through pro-inflammatory cytokines that activate the tryptophan-kynurenine pathway, regulate serotonin production and N-methyl-D-aspartate (NMDA) receptor activity, and may also indirectly affect dopamine regulation (Dantzer et al., 2008)
Recovering From Injury
What is not so good is that, as the great review study about vitamin C derivatives in the Journal of Cosmetic Dermatology writes, MAP is "at very best, poorly absorbed in comparison to AA." Moreover, derivatives not only have to be absorbed into the skin, they also have to be converted into pure AA
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